Using high-throughput approaches to unveil sporulation and germination mechanisms in Clostridium sporogenes
Intravenously injected clostridial spores infiltrate and selectively germinate in the hypoxic regions of solid tumours. The exquisite selectivity of this natural phenomenon is being exploited to bring about tumour destruction by engineering the delivered clostridia to enzymatically convert a subsequ...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/59874/ |