Investigation of protein arginine methyltransferase bisubstrate inhibitors
Protein arginine methylation is a significant post-translational modification which is catalysed by protein arginine methyltransferases (PRMTs). PRMTs catalyse the transfer of methyl group from the cofactor S-adenosyl-L-methionine (SAM) to arginine residues which are present in proteins. Dysregulati...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/59769/ |