Targeting thioredoxin system to improve radiotherapeutic response of brain cancers

QR Code

Targeting thioredoxin system to improve radiotherapeutic response of brain cancers

Radiotherapy is often prescribed for brain cancer, particularly high-grade malignant gliomas. Efficacy is, however, often limited by radioresistance. The thioredoxin (Trx) system, a key antioxidant pathway in defence against oxidative stress, represents a potentially attractive target to overcome su...

Full description

Bibliographic Details
Main Author:	Yao, Anqi
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Online Access:	https://eprints.nottingham.ac.uk/59516/

Similar Items

The role of redox proteins in the radiotherapeutic response of breast cancer
by: Abdullah, Nurul Akmaryanti
Published: (2019)

Targeting thioredoxin reductase in pancreatic cancer
by: Alhadyan, Khaled
Published: (2019)

Thioredoxin system in colorectal cancer: Its role in carcinogenesis, disease progression, and response to treatment
by: Abdullah, Nurul Akmaryanti, et al.
Published: (2024)

Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer
by: Abdullah, Nurul Akmaryanti, et al.
Published: (2021)

Albumin fusion of thioredoxin - The production and evaluation of its biological activity for potential therapeutic applications
by: Ikuta, S., et al.
Published: (2010)

Thioredoxin interacting protein (TXNIP) is an independent risk stratifier for breast ductal carcinoma in situ
by: Miligy, Islam, et al.
Published: (2018)

Targeted therapy for cancer using pH-responsive nanocarrier systems
by: Manchun, S., et al.
Published: (2012)

A human serum albumin–thioredoxin fusion protein prevents experimental contrast-induced nephropathy
by: Kodama, A., et al.
Published: (2013)

Albumin fusion prolongs the antioxidant and anti-inflammatory activities of thioredoxin in mice with acetaminophen-induced hepatitis
by: Tanaka, R., et al.
Published: (2014)

Targeting brain-eating amoebae infections
by: Khan, Naveed Ahmed *, et al.
Published: (2017)

Thioredoxin-albumin fusion protein prevents copper enhanced zinc-induced neurotoxicity via its antioxidative activity
by: Tanaka, K., et al.
Published: (2018)

Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression
by: Tanaka, R., et al.
Published: (2013)

Therapeutic impact of human serum albumin-thioredoxin fusion protein on influenza virus-induced lung injury mice
by: Tanaka, R., et al.
Published: (2014)

Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury
by: Furukawa, M., et al.
Published: (2011)

Albumin fusion renders thioredoxin an effective anti-oxidative and anti-inflammatory agent for preventing cisplatin-induced nephrotoxicity
by: Kodama, A., et al.
Published: (2014)

Targeting DNA repair and hypoxia to improve radioresponse in breast cancer
by: Aiyappa, Radhika
Published: (2020)

Role of calpain in breast cancer and regulation of therapeutic response to targeted treatment
by: Pu, Xuan
Published: (2016)

Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy
by: Bouzinab, Kaouthar
Published: (2021)

Targeting platelets for the treatment of cancer
by: Elaskalani, Omar, et al.
Published: (2017)

Targeting PDK1 in cancer
by: Raimondi, C., et al.
Published: (2011)

Improved Composite Table Algorithm for targeting regeneration-recycle water network
by: Parand, Reza, et al.
Published: (2015)

Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1
by: Yu, Yu, et al.
Published: (2011)

Renoprotective effect of long acting thioredoxin by modulating oxidative stress and macrophage migration inhibitory factor against rhabdomyolysis-Associated acute kidney injury
by: Nishida, K., et al.
Published: (2015)

The effect of ageing on the blood-brain barrier: The potential of nanoparticle drug delivery systems to target cerebrovascular changes
by: Bates, Jessica
Published: (2025)

Characterization of Phosphorylated Targets in Ovarian Cancer
by: Binju, Mudra
Published: (2024)

Cancer-associated membrane protein as targeted therapy for bladder cancer
by: Roslan, Adlina, et al.
Published: (2022)

In silico prediction and validation of Gfap as miR-3099 target in the mouse brain
by: Zainal Abidin, Shahidee, et al.
Published: (2017)

A case-based reasoning system for radiotherapy treatment planning for brain cancer
by: Jagannathan, Rupa
Published: (2013)

Bio-responsive hydrogels for an in vitro brain cancer cell model: self-controlled inhibition of matrix metalloproteinase activity
by: Russo, Emanuele
Published: (2020)

The use of thermoresponsive nanoparticles for targeting cancer cells
by: MOIR, LEE A
Published: (2016)

Polyadenylation as a target for the treatment of breast cancer
by: Thiyab, Asraa
Published: (2025)

Targeting energy metabolism to eliminate cancer cells
by: Shahruzaman, Shazwin Hani, et al.
Published: (2018)

Molecular targets and anti-cancer potential of escin
by: Cheong, D., et al.
Published: (2018)

Targeting PDK1 for Chemosensitization of Cancer Cells.
by: Emmanouilidi, A., et al.
Published: (2017)

Cancer stem cell metabolism: A potential target for cancer therapy
by: Deshmukh, A., et al.
Published: (2016)

Targeting improved partial resistance using yield-loss response curves for foliar diseases of wheat
by: Shankar, Manisha, et al.
Published: (2020)

What Factors Determine the Choices between Joint Venture and Wholly Owned Subsidiary? Experience from China's FMCG Industry
by: SHAO, ANQI
Published: (2011)

Factors Influencing Consumer-Perceived Risk in E-Commerce Transactions in China
by: Zheng, Anqi
Published: (2012)

The Representation of Ideal Beauty in Advertising--A longitudinal study of No.7
by: GU, ANQI
Published: (2017)

The impact of the Covid-19 Pandemic on earnings management - Evidence from listed companies in China
by: Du, Anqi
Published: (2022)