Targeting thioredoxin system to improve radiotherapeutic response of brain cancers
Radiotherapy is often prescribed for brain cancer, particularly high-grade malignant gliomas. Efficacy is, however, often limited by radioresistance. The thioredoxin (Trx) system, a key antioxidant pathway in defence against oxidative stress, represents a potentially attractive target to overcome su...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2020
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| Online Access: | https://eprints.nottingham.ac.uk/59516/ |