Investigating the mode of action of intracellular loop 1 pepducins at the CXCR4 receptor
Background Pepducins are lipid-peptides derived from the intracellular loop sequences of a G protein-coupled receptor and have been shown to act as allosteric modulators. Pepducins have been described for the chemokine receptor, CXCR4, which can exhibit agonist activity in the absence of the endog...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
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| Online Access: | https://eprints.nottingham.ac.uk/59351/ |