Examining the substrate scope of transaminase variants derived from Vibrio fluvialis

This work builds on previous work from the O’Reilly group. Bulky ketoenone and diketone substrates structurally preorganised to undergo cyclisation after transamination were synthesised and tested with a panel of transaminases. Particular attention was paid to transaminases engineered for the accept...

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Bibliographic Details
Main Author: Peel, Christopher
Format: Thesis (University of Nottingham only)
Language:English
Published: 2019
Subjects:
Online Access:https://eprints.nottingham.ac.uk/59327/