Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics

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Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics

The dopamine (DA) D1 and D2 receptors (D1R and D2R, respectively) are G protein-coupled receptors (GPCRs) that are therapeutic targets for the symptomatic treatment of neurological disorders such as schizophrenia (SCZ) and Parkinson’s disease (PD). Classical approaches to GPCR drug discovery have fo...

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Bibliographic Details
Main Author:	Fyfe, Tim
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	dopamine receptors drug-receptor interactions central nervous system diseases
Online Access:	https://eprints.nottingham.ac.uk/57344/

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