Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics
The dopamine (DA) D1 and D2 receptors (D1R and D2R, respectively) are G protein-coupled receptors (GPCRs) that are therapeutic targets for the symptomatic treatment of neurological disorders such as schizophrenia (SCZ) and Parkinson’s disease (PD). Classical approaches to GPCR drug discovery have fo...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2019
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| Online Access: | https://eprints.nottingham.ac.uk/57344/ |