Structural Investigation of Zn2+ ions, FXII and Complement receptor gC1q-R interaction: Triggering the Contact activation System

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Structural Investigation of Zn2+ ions, FXII and Complement receptor gC1q-R interaction: Triggering the Contact activation System

The contact activation system or CAS, is an important process that contributes in immunity, inflammation and thrombosis. Contact activation is triggered when coagulation FXII (FXII) and High molecular weight kininogen (HK) bound to Prekallikrein (PK) dock on the surface of complement receptor gC1q-R...

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Bibliographic Details
Main Author:	Kaira, Bubacarr
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	contact activation system CAS inflammation binding sites
Online Access:	https://eprints.nottingham.ac.uk/57187/

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