Pain behaviour, locomotor activity, inflammation and muscle metabolic dysregulation in pre-clinical animal models of OA and RA and the impact of PPARɣ agonism intervention

Background: Osteoarthritis (OA) and rheumatoid arthritis (RA) are degenerative joint diseases accompanied by pain and inflammation, which can lead to a sedentary lifestyle. Skeletal muscle inflammation and inactivity can lead to increased muscle insulin resistance and atrophy, which are associated w...

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Bibliographic Details
Main Author: Casanova, Nuria
Format: Thesis (University of Nottingham only)
Language:English
Published: 2019
Subjects:
Online Access:https://eprints.nottingham.ac.uk/56730/