The role of gfi1b in zebrafish thrombopoiesis
gfi1b is a member of the gfi1 family of genes which encode zinc finger transcriptional repressors that are involved in regulating haematopoiesis. In mammals it has been shown that the loss of gfi1b function causes defects in megakaryocyte maturation, leading to the inability to produce platelets. Th...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2019
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| Online Access: | https://eprints.nottingham.ac.uk/56567/ |