Investigating the venom components of the Giant Indian Centipede for Nav1.7 channel modifiers

The electro-genesis property of voltage-gated sodium channels makes them indispensable therapeutic targets for numerous conductance disorders. The sodium channel (NaV)1.7 subtype expressed in sensory neurons in the dorsal root ganglia is thought to be a crucial signaling protein involved in nocicept...

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Bibliographic Details
Main Author: Ngum, Neville Mvo
Format: Thesis (University of Nottingham only)
Language:English
Published: 2019
Subjects:
Online Access:https://eprints.nottingham.ac.uk/56537/