Nickel-catalysed synthesis of multisubstituted pyrroles by anti-carbometallative cyclisations
Herein is presented the first example of nickel-catalysed cyclisation of Ntosylalkynamides with arylboronic acids to give 2,3,4-trisubstituted pyrroles. The reaction is initiated by alkyne arylnickelation and proceeds via an essential E/Z isomerisation step which allows for cyclisation. An investiga...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/56140/ |