Investigation of CRISPR-Cas adaptation mechanism through exploration of Cas4-1 fusions

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Investigation of CRISPR-Cas adaptation mechanism through exploration of Cas4-1 fusions

CRISPR-Cas is an adaptive immune system present in bacteria and archaea. It involves two linked stages: adaptation and interference. Adaptation generates a database of mobile genetic element sequences within a CRISPR locus through ‘capture’ of DNA fragments by Cas1-Cas2 and integration into the CRIS...

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Bibliographic Details
Main Author:	Walker, Emily
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	CRISPR adaptation; Cas4-1
Online Access:	https://eprints.nottingham.ac.uk/56071/

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