Metabolic regulation and consequences of an altered microenvironment in cancer cell lines
Tumours are commonly associated with a shift in cellular metabolism to establish an acidic microenvironment that is further exacerbated by hypoxia. Such changes in extracellular pH (pHe) and oxygen tension (PO2) alter ion homeostasis effecting cancer hallmarks. High intracellular potassium (K+) is a...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/55919/ |