Synthesis of pyrroles by nickel-catalysed arylative cyclisations of alkynamides
A nickel-based catalytic system for the anti-carbometallative cyclisations of alkynamides to arylboronic acids is described. The reactions proceed using catalytic nickel and (rac)-Ph-PHOX, to provide alkenylnickel species which can undergo reversible E/Z-isomerisation, followed by cyclisation onto a...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
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| Online Access: | https://eprints.nottingham.ac.uk/55874/ |