Combatting chemoresistance: an analysis of DNA repair proteins ERCC1 and XPF and their chemotherapeutic implications in ovarian cancer

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Combatting chemoresistance: an analysis of DNA repair proteins ERCC1 and XPF and their chemotherapeutic implications in ovarian cancer

Platinum-based drugs form a key aspect of multimodal treatment to various cancers. Despite this, resistance to platinum therapy is a colossal threat encircling the treatment of ovarian cancers. It is well documented that an upregulation in DNA repair pathways is an advantageous characteristic for ca...

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Bibliographic Details
Main Author:	Griffin, Michaela
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	Chemoresistance Olaparib Cisplatin ERCC1 XPF DNA Repair Nucleotide Excision Repair Ovarian Cancer Cancer treatment Chemotherapy
Online Access:	https://eprints.nottingham.ac.uk/55788/

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