Combatting chemoresistance: an analysis of DNA repair proteins ERCC1 and XPF and their chemotherapeutic implications in ovarian cancer
Platinum-based drugs form a key aspect of multimodal treatment to various cancers. Despite this, resistance to platinum therapy is a colossal threat encircling the treatment of ovarian cancers. It is well documented that an upregulation in DNA repair pathways is an advantageous characteristic for ca...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2019
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| Online Access: | https://eprints.nottingham.ac.uk/55788/ |