Investigating a key autophagy protein-protein interaction and its modulation by phosphorylation and an ALS-related mutation
Autophagy is a cellular degradation pathway which removes cytoplasmic material including protein aggregates, damaged organelles and pathogens. The interaction of the autophagy adaptor p62 with lipid-anchored hAtg8 receptor proteins is a key step in this process whereby cargo bound to p62 is sequeste...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/55747/ |