Modulatory effect of mild inflammation on tau phosphorylation in a human tau mouse model of Alzheimer's disease

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Modulatory effect of mild inflammation on tau phosphorylation in a human tau mouse model of Alzheimer's disease

Alzheimer’s disease (AD) is the most common form of dementia and involves the pathological hyperphosphorylation and aggregation of the microtubule associated protein tau. Aetiological evidence, and evidence from post-mortem studies, suggests neuroinflammation to be an early mechanistic driver of AD....

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Bibliographic Details
Main Author:	Barron, Matthew
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	Alzheimer's disease; Hyperphosphorylation; Tau pathology; Inflammation; Animal models
Online Access:	https://eprints.nottingham.ac.uk/55558/

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