Modulatory effect of mild inflammation on tau phosphorylation in a human tau mouse model of Alzheimer's disease
Alzheimer’s disease (AD) is the most common form of dementia and involves the pathological hyperphosphorylation and aggregation of the microtubule associated protein tau. Aetiological evidence, and evidence from post-mortem studies, suggests neuroinflammation to be an early mechanistic driver of AD....
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2018
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| Online Access: | https://eprints.nottingham.ac.uk/55558/ |