Studying relationship between increased 5-methylcytosine oxidation and expression of cancer stem cell markers in glioblastoma cell lines

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Studying relationship between increased 5-methylcytosine oxidation and expression of cancer stem cell markers in glioblastoma cell lines

DNA methylation (5-methylcytosine, 5mC) is an epigenetic modification generated by the addition of a methyl group to the 5 position on the cytosine ring of the DNA and it is important for a range of biological processes such as development and chromosome stability. 5mC can be enzymatically oxidised...

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Bibliographic Details
Main Author:	Wijeyagumar, Vithusha
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	DNA methylation; Brain tumour cell lines; Glioblastoma cells
Online Access:	https://eprints.nottingham.ac.uk/55512/

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