Studying relationship between increased 5-methylcytosine oxidation and expression of cancer stem cell markers in glioblastoma cell lines
DNA methylation (5-methylcytosine, 5mC) is an epigenetic modification generated by the addition of a methyl group to the 5 position on the cytosine ring of the DNA and it is important for a range of biological processes such as development and chromosome stability. 5mC can be enzymatically oxidised...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2018
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| Online Access: | https://eprints.nottingham.ac.uk/55512/ |