SUMOylation of Sox2 in neural stem cells

Sox2 plays a crucial role in the biology of neural stem cells (NSC) by regulating differentiation and keeping NSC in a slowly proliferative state which allows to maintain over time a pool of stem cells ready to differentiate in more rapidly dividing progenitor cells. Sox2 exerts these functions by t...

Full description

Bibliographic Details
Main Author: Marelli, Elisa
Format: Thesis (University of Nottingham only)
Language:English
Published: 2018
Subjects:
Online Access:https://eprints.nottingham.ac.uk/55312/