Application of “smart” amine donors for rapid screening and scale-up of transaminase-mediated biotransformations
The “smart” amine donors o‐xylylenediamine and cadaverine were employed for the rapid screening of a large ketone library and subsequent preparative‐scale synthesis of selected compounds using a commercially available amine transaminase, ATA256. The methodology enables both screening and preparative...
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Bibliographic Details
| Main Authors: |
Gomm, Andrew,
Grigoriou, Stylianos,
Peel, Christopher,
Ryan, James,
Mujtaba, Nafees,
Clarke, Thomas,
Kulcinskaja, Evelina,
O'Reilly, Elaine |
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| Format: | Article
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| Language: | English |
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| Published: |
Wiley
2018
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| Online Access: | https://eprints.nottingham.ac.uk/53766/
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