Screening for inhibitors of Staphylococcal Sortase A as novel anti-infective agents
Staphylococcus aureus is a Gram-positive human pathogen that has developed resistance to all traditionally used antibiotics. Sortase A (SrtA) is a ‘house-keeping’ enzyme present in a number of Gram-positive organisms including S. aureus that is responsible for the covalent anchoring of proteins to t...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2018
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| Online Access: | https://eprints.nottingham.ac.uk/53236/ |