Age differences in head motion and estimates of cortical morphology

Cortical morphology is known to differ with age, as measured by cortical thickness, fractal dimensionality, and gyrification. However, head motion during MRI scanning has been shown to influence estimates of cortical thickness as well as increase with age. Studies have also found task-related differ...

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Main Author: Madan, Christopher R.
Format: Article
Published: PeerJ 2018
Subjects:
Online Access:https://eprints.nottingham.ac.uk/53175/
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author Madan, Christopher R.
author_facet Madan, Christopher R.
author_sort Madan, Christopher R.
building Nottingham Research Data Repository
collection Online Access
description Cortical morphology is known to differ with age, as measured by cortical thickness, fractal dimensionality, and gyrification. However, head motion during MRI scanning has been shown to influence estimates of cortical thickness as well as increase with age. Studies have also found task-related differences in head motion and relationships between body–mass index (BMI) and head motion. Here I replicated these prior findings, as well as several others, within a large, open-access dataset (Centre for Ageing and Neuroscience, CamCAN). This is a larger dataset than these results have been demonstrated previously, within a sample size of more than 600 adults across the adult lifespan. While replicating prior findings is important, demonstrating these key findings concurrently also provides an opportunity for additional related analyses: critically, I test for the influence of head motion on cortical fractal dimensionality and gyrification; effects were statistically significant in some cases, but small in magnitude.
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spelling nottingham-531752020-05-04T19:47:26Z https://eprints.nottingham.ac.uk/53175/ Age differences in head motion and estimates of cortical morphology Madan, Christopher R. Cortical morphology is known to differ with age, as measured by cortical thickness, fractal dimensionality, and gyrification. However, head motion during MRI scanning has been shown to influence estimates of cortical thickness as well as increase with age. Studies have also found task-related differences in head motion and relationships between body–mass index (BMI) and head motion. Here I replicated these prior findings, as well as several others, within a large, open-access dataset (Centre for Ageing and Neuroscience, CamCAN). This is a larger dataset than these results have been demonstrated previously, within a sample size of more than 600 adults across the adult lifespan. While replicating prior findings is important, demonstrating these key findings concurrently also provides an opportunity for additional related analyses: critically, I test for the influence of head motion on cortical fractal dimensionality and gyrification; effects were statistically significant in some cases, but small in magnitude. PeerJ 2018-07-27 Article PeerReviewed Madan, Christopher R. (2018) Age differences in head motion and estimates of cortical morphology. PeerJ . e5176. ISSN 2167-8359 Head motion Cortical structure Fractal dimensionality Age Cortical thickness Gyrification Cortical morphology Movie watching BMI https://peerj.com/articles/5176/ doi:10.7717/peerj.5176 doi:10.7717/peerj.5176
spellingShingle Head motion
Cortical structure
Fractal dimensionality
Age
Cortical thickness
Gyrification
Cortical morphology
Movie watching
BMI
Madan, Christopher R.
Age differences in head motion and estimates of cortical morphology
title Age differences in head motion and estimates of cortical morphology
title_full Age differences in head motion and estimates of cortical morphology
title_fullStr Age differences in head motion and estimates of cortical morphology
title_full_unstemmed Age differences in head motion and estimates of cortical morphology
title_short Age differences in head motion and estimates of cortical morphology
title_sort age differences in head motion and estimates of cortical morphology
topic Head motion
Cortical structure
Fractal dimensionality
Age
Cortical thickness
Gyrification
Cortical morphology
Movie watching
BMI
url https://eprints.nottingham.ac.uk/53175/
https://eprints.nottingham.ac.uk/53175/
https://eprints.nottingham.ac.uk/53175/