Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth

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Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth

Previously, we highlighted induction of an integrated stress response (ISR) gene program in skeletal muscle of pigs treated with a beta-adrenergic agonist. Hence we tested the hypothesis that the ER-stress inhibitor, sodium 4-phenylbutyrate (PBA), would inhibit Clenbuterol-mediated muscle growth and...

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Bibliographic Details
Main Authors:	Brown, David M., Jones, Sarah, Daniel, Zoe C.T.R., Brearley, Madelaine C., Lewis, Jo E., Ebling, Francis J.P., Parr, Tim, Brameld, John M.
Format:	Article
Published:	Public Library of Science 2018
Subjects:	Integrated stress response beta-adrenergic agonist ER-stress hypertrophy atrophy activating transcription factor
Online Access:	https://eprints.nottingham.ac.uk/53139/

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