Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth

Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth

Previously, we highlighted induction of an integrated stress response (ISR) gene program in skeletal muscle of pigs treated with a beta-adrenergic agonist. Hence we tested the hypothesis that the ER-stress inhibitor, sodium 4-phenylbutyrate (PBA), would inhibit Clenbuterol-mediated muscle growth and...

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Bibliographic Details
Main Authors: Brown, David M., Jones, Sarah, Daniel, Zoe C.T.R., Brearley, Madelaine C., Lewis, Jo E., Ebling, Francis J.P., Parr, Tim, Brameld, John M.
Format: Article
Published: Public Library of Science 2018
Subjects:
Integrated stress response
beta-adrenergic agonist
ER-stress
hypertrophy
atrophy
activating transcription factor
Online Access:https://eprints.nottingham.ac.uk/53139/

Internet

https://eprints.nottingham.ac.uk/53139/

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