Au(I) N-heterocyclic carbenes from bisimidazolium amphiphiles: synthesis, cytotoxicity and incorporation onto gold nanoparticles

A gold(I) N-heterocyclic carbene 4 from a bis-imidazolium-amphiphile was synthesized and characterized. The cytotoxicity against HT-29 colon carcinoma and MDA-MB-231 breast adenocarcinoma cells was assessed for the NHC complex 4, the imidazolium salt precursor 2, and its methyl analogue 3, indicatin...

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Bibliographic Details
Main Authors: Rodrigues, Mafalda, Russo, Lorenzo, Aguilo, E., Rodriguez, L., Ott, I., Pérez-García, Lluïsa
Format: Article
Published: Royal Society of Chemistry 2015
Online Access:https://eprints.nottingham.ac.uk/52915/