A fellowship of Ring1 maintains AML stem cells

Polycomb repressive complex 1 (PRC1) and PRC2 are transcriptional repressors that function as key regulators of the self-renewal and differentiation (cell lineage specification) pathways in stem cells. In this issue of Blood, Shima et al1 report that 2 ubiquitin ligases (Ring1A and Ring1B), which ar...

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Bibliographic Details
Main Author: Heery, David M.
Format: Article
Language:English
English
Published: American Society of Hematology 2018
Online Access:https://eprints.nottingham.ac.uk/52899/