Effects of VEGF-A165b and SRPK1 inhibition on pain behaviour, cyclooxygenase expression and glial activation in the CNS in a model of osteoarthritis

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Effects of VEGF-A165b and SRPK1 inhibition on pain behaviour, cyclooxygenase expression and glial activation in the CNS in a model of osteoarthritis

Background: Osteoarthritis (OA) is the most common musculoskeletal disease worldwide and a major cause of chronic pain. Treatment of OA pain is still suboptimal due to limited efficacy and considerable side effects of available analgesics. Pain in OA has a significant central component. Cyclooxygena...

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Bibliographic Details
Main Author:	Almahasneh, Fatimah
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	pain osteoarthritis VEGF-A165b SRPK1
Online Access:	https://eprints.nottingham.ac.uk/52753/

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