Effects of VEGF-A165b and SRPK1 inhibition on pain behaviour, cyclooxygenase expression and glial activation in the CNS in a model of osteoarthritis
Background: Osteoarthritis (OA) is the most common musculoskeletal disease worldwide and a major cause of chronic pain. Treatment of OA pain is still suboptimal due to limited efficacy and considerable side effects of available analgesics. Pain in OA has a significant central component. Cyclooxygena...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2018
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| Online Access: | https://eprints.nottingham.ac.uk/52753/ |