Evolution of pluripotency: hijacking of an ancient network

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Evolution of pluripotency: hijacking of an ancient network

Pluripotency is conserved in the major trunk of Vertebrate evolution, but how the gene regulatory network (GRN) that governs it evolved is poorly understood. A central component of this network is the Homeodomain containing transcription factor Nanog. How Nanog evolved is not understood, as Nanog s...

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Bibliographic Details
Main Author:	Crowley, Darren Jerome
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Online Access:	https://eprints.nottingham.ac.uk/52197/

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