Function of MYST3 / MOZ: a histone acetyltransferase and chromatin regulator implicated in haematopoietic stem cell development and leukaemia

MOZ (also known as KAT6A and MYST3) is a histone acetyltransferase that is implicated in the development of hematopoietic, heart and craniofacial tissues. Reciprocal translocations generating MOZ fusion proteins are associated with acute myeloid leukaemia (AML), a heterogeneous hematopoietic stem ce...

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Bibliographic Details
Main Author: Monteiro, C.J.
Format: Thesis (University of Nottingham only)
Language:English
Published: 2018
Online Access:https://eprints.nottingham.ac.uk/52018/