Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis
Background: Inflammation is an essential component of arthritis pain. Nerve growth factor (NGF) plays a key role in acute and chronic pain states especially those associated with inflammation. NGF acts through tropomyosin-receptor-kinase A (TrkA). NGF blockade has reduced arthritis pain in clinical...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
BioMed Central Ltd
2016
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/51914/ |