Enantioselective nickel-catalyzed arylative intramolecular 1,4allylations

The enantioselective nickel-catalyzed desymmetrization of allenyl cyclohexa-2,5-dienones by reaction with arylboronic acids is described. Nickel-catalyzed arylation of the allene gives allylnickel species, which undergo cyclization by 1,4allylation to produce hexahydroindol-5-ones and hexahydrofuran...

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Bibliographic Details
Main Authors: Nguyen, Thi Le Nhon, Incerti-Pradillos, Celia A., Lewis, William, Lam, Hon Wai
Format: Article
Published: Royal Society of Chemistry 2018
Online Access:https://eprints.nottingham.ac.uk/51692/