Pharmacogenomics of drug-induced liver injury (DILI): molecular biology to clinical applications

Pharmacogenomics of drug-induced liver injury (DILI): molecular biology to clinical applications

A number of drug-specific and host-related factors contribute to the development of drug-induced liver injury (DILI). Investigations focused on genetic susceptibility to DILI have advanced our understanding of the pathogenesis of this rare, yet potentially life-threatening adverse reaction. Candidat...

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Bibliographic Details
Main Authors: Kaliyaperumal, Kalaiyarasi, Grove, Jane I., Delahay, Robin M., Griffiths, William. J.H., Duckworth, Adam, Aithal, Guruprasad P.
Format: Article
Published: Elsevier 2018
Subjects:
Drug-induced liver injury (DILI); Amoxicillin-clavulanic acid; HLA-DRB1*15:02; Major Histocompatibility Complex (MHC); Peptide-binding groove; diagnostic; genotyping
Online Access:https://eprints.nottingham.ac.uk/51566/

Internet

https://eprints.nottingham.ac.uk/51566/

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