Hippocampal TET1 and TET2 expression and DNA hydroxymethylation are affected by physical exercise in aged mice
The function of 5-hydroxymethylcytosine (5hmC) is poorly understood. 5hmC is an epigenetic modification of DNA, resulting from the oxidation of 5-methylcytosine (5mC) by the Fe2+, and 2-oxoglutarate-dependent, 10–11 translocation methylcytosine dioxygenases (TET1, TET2, and TET3). Recent evidence su...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51371/ |