The identification of STAT2 as a pervasive negative regulator of STAT1 activity and cytokine signalling

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The identification of STAT2 as a pervasive negative regulator of STAT1 activity and cytokine signalling

Interferons (IFNs) are cytokines which play a crucial role in the host defence against pathogens through the upregulation of hundreds of target genes. The binding of an IFN molecule to its specific receptor, results in the tyrosine phosphorylation of a member of the Signal Transducer and Activator o...

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Bibliographic Details
Main Author:	Ho, Johnathan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	STAT2 STAT1 Interferon IFN Cell Signalling Immune Response
Online Access:	https://eprints.nottingham.ac.uk/51263/

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