The identification of STAT2 as a pervasive negative regulator of STAT1 activity and cytokine signalling
Interferons (IFNs) are cytokines which play a crucial role in the host defence against pathogens through the upregulation of hundreds of target genes. The binding of an IFN molecule to its specific receptor, results in the tyrosine phosphorylation of a member of the Signal Transducer and Activator o...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2018
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| Online Access: | https://eprints.nottingham.ac.uk/51263/ |