A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug
interactions

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A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions

All pharmaceutical companies are required to assess pharmacokinetic drug-drug interactions (DDIs) of new chemical entities (NCEs) and mathematical prediction helps to select the best NCE candidate with regard to adverse effects resulting from a DDI before any costly clinical studies. Most current mo...

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Bibliographic Details
Main Authors:	Cherkaoui-Rbati, Mohammed, Paine, Stuart, Littlewood, Peter, Rauch, Cyril
Format:	Article
Published:	Public Library of Science 2017
Online Access:	https://eprints.nottingham.ac.uk/51258/

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