A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions
All pharmaceutical companies are required to assess pharmacokinetic drug-drug interactions (DDIs) of new chemical entities (NCEs) and mathematical prediction helps to select the best NCE candidate with regard to adverse effects resulting from a DDI before any costly clinical studies. Most current mo...
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Public Library of Science
2017
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| Online Access: | https://eprints.nottingham.ac.uk/51258/ |