Design, synthesis, and characterisation of small molecule inhibitors of the coagulation factor XIIa (FXIIa)
Thromboembolic disorders are the major cause of death and disability worldwide. Anticoagulants are the mainstay in the prevention and treatment of thromboembolic diseases. However, almost all the currently available anticoagulants cause therapy-related haemorrhages as a side effect. In the recent ye...
| Main Author: | Hussein, Ali Hasson |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/50895/ |
Similar Items
Design and synthesis of small molecule inhibitors of coagulation FXIIa
by: Chen, Xi
Published: (2018)
by: Chen, Xi
Published: (2018)
Crystallographic studies of coagulation factor XII
by: Manna, Rosa
Published: (2016)
by: Manna, Rosa
Published: (2016)
Expression and modulation of tissue factor and tissue factor pathway inhibitor in an endothelial cell based model
by: Ellery, Paul E. R.
Published: (2008)
by: Ellery, Paul E. R.
Published: (2008)
Extraction and characterization of Jatropha curcas L. as natural coagulant and its application for turbidity removal
by: Khodapanah, Nasrin
Published: (2014)
by: Khodapanah, Nasrin
Published: (2014)
Coagulation of colloidal raw water with Kaolin for water/Siti Rahayu Mohamed
by: Mohamed, Siti Rahayu
Published: (2009)
by: Mohamed, Siti Rahayu
Published: (2009)
Removal Of Arsenic From Water Using Natural Coagulant (Moringa Oliefera)
by: Mezughi, Khaled M
Published: (2003)
by: Mezughi, Khaled M
Published: (2003)
Structural studies of FXII and associated proteins
by: Brown, Alexander
Published: (2023)
by: Brown, Alexander
Published: (2023)
Coagulation equations with mass loss
by: Wattis, Jonathan A.D., et al.
Published: (2004)
by: Wattis, Jonathan A.D., et al.
Published: (2004)
Risk of venous thromboembolism during and after hospitalisation in patients with inflammatory bowel disease activity
by: Chu, Thomas P.C., et al.
Published: (2018)
by: Chu, Thomas P.C., et al.
Published: (2018)
Development of a new recombinant starter culture bacterium for milk coagulation
by: Raftari, Mohammad
Published: (2013)
by: Raftari, Mohammad
Published: (2013)
Synergistic effect of biological activated carbon and enhanced coagulation in secondary wastewater effluent treatment
by: Aryal, Ashok, et al.
Published: (2012)
by: Aryal, Ashok, et al.
Published: (2012)
An introduction to mathematical models of
coagulation-fragmentation processes:
a discrete deterministic mean-field approach
by: Wattis, Jonathan A.D.
Published: (2006)
by: Wattis, Jonathan A.D.
Published: (2006)
Effects of coagulants, processing variables and milky extract of kenaf seed-to-soybean ratios on the physicochemical property and texture profile of kenaf (Hibiscus cannabinus L.) seed-based tofu
by: Giwa, Ibrahim Shafa'atu
Published: (2021)
by: Giwa, Ibrahim Shafa'atu
Published: (2021)
Mathematical Modelling of Mechanical Alloying
by: Harris, John Richard
Published: (2002)
by: Harris, John Richard
Published: (2002)
Coagulation Performance of Moringa Oleifera Seeds Stored Under Different Preservation Conditions
by: Ng, Shu Chin
Published: (2006)
by: Ng, Shu Chin
Published: (2006)
Evidence that BAC treatment enhances the DOC Removal by enhanced coagulation
by: Aryal, Ashok, et al.
Published: (2011)
by: Aryal, Ashok, et al.
Published: (2011)
Effect of suspended solids in secondary wastewater effluent on DOC removal by enhanced coagulation
by: Aryal, Ashok, et al.
Published: (2011)
by: Aryal, Ashok, et al.
Published: (2011)
Blood clotting profiles of haruan fish (channa striatus sp.) aqueous extract
by: Soo, Kuan Meng
Published: (2012)
by: Soo, Kuan Meng
Published: (2012)
Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study
by: Humes, D.J., et al.
Published: (2018)
by: Humes, D.J., et al.
Published: (2018)
Synthesis, Characterization and Application of Polyacrylamide Grafted Sago Strach for Coagulation and Flocculation Processes
by: M. Qudsieh, Isam Yassin
Published: (2006)
by: M. Qudsieh, Isam Yassin
Published: (2006)
Risk of venous thromboembolism in hospitalised cancer patients in England – A cohort study
by: Ratib, Sonia, et al.
Published: (2016)
by: Ratib, Sonia, et al.
Published: (2016)
Venous thromboembolism in children with cancer – a population-based cohort study
by: Walker, Alex J., et al.
Published: (2014)
by: Walker, Alex J., et al.
Published: (2014)
Spontaneous central venous thrombosis and shunt occlusion following peritoneovenous shunt placement for intractable ascites
by: Hariharan, D., et al.
Published: (2017)
by: Hariharan, D., et al.
Published: (2017)
Mitochondrial gene expression is required for platelet function and blood clotting
by: Richman, T.R., et al.
Published: (2023)
by: Richman, T.R., et al.
Published: (2023)
The potential of wheat germs as a coagulant to
treat batik wastewater / Nurhaslina C.R, Ku Halim Ku Hamid and Siti Zuraida Mohamad
by: C.R, Nurhaslina, et al.
Published: (2011)
by: C.R, Nurhaslina, et al.
Published: (2011)
Risk of venous thromboembolism in children after general surgery
by: Humes, David J., et al.
Published: (2015)
by: Humes, David J., et al.
Published: (2015)
Effects of organo-floc as natural coagulant on posttreatment of ultrafiltration membrane
by: Ahmad, Mohd Azwan, et al.
Published: (2016)
by: Ahmad, Mohd Azwan, et al.
Published: (2016)
A study of hybrid clarification-filtration processes for potable water treatment
by: Price, Robert
Published: (2005)
by: Price, Robert
Published: (2005)
Coarse-graining and renormalisation group methods for the elucidation of the kinetics of complex nucleation and growth processes
by: Coveney, Peter V., et al.
Published: (2006)
by: Coveney, Peter V., et al.
Published: (2006)
Study on the adsorption of pb(ii) onto citric acid and monosodium glutamate modified rubber leaf powder / Ahmad Faisal Fadzil
by: Fadzil, Ahmad Faisal
Published: (2014)
by: Fadzil, Ahmad Faisal
Published: (2014)
Evaluation of turbidity removal using Moringa oleifera lam. seeds
by: Bagh, Mohammad Golestan
Published: (2010)
by: Bagh, Mohammad Golestan
Published: (2010)
Risk of venous thromboembolism in people with lung cancer: a cohort study using linked UK healthcare data
by: Walker, Alex J., et al.
Published: (2016)
by: Walker, Alex J., et al.
Published: (2016)
Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules
by: Zhang, W., et al.
Published: (2021)
by: Zhang, W., et al.
Published: (2021)
Powdered activated carbon coupled with enhanced coagulation for natural organic matter removal and disinfection by-product control: Application in a Western Australian water treatment plant
by: Kristiana, Ina, et al.
Published: (2011)
by: Kristiana, Ina, et al.
Published: (2011)
Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation
by: Hamad, Badraldin K., et al.
Published: (2017)
by: Hamad, Badraldin K., et al.
Published: (2017)
Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors
by: Murray, Ewan J., et al.
Published: (2014)
by: Murray, Ewan J., et al.
Published: (2014)
Screening For Small Molecule Inhibitors Of p27Kip1 Degradation
by: Ooi, Li Ching
Published: (2012)
by: Ooi, Li Ching
Published: (2012)
Synthesis, characterisation and biological activities of mixed-ligand copper(II) complexes containing saccharin as one of the ligands
by: Begum, Thahira
Published: (2005)
by: Begum, Thahira
Published: (2005)
Physiological characteristics associated with increased resistance to decompression sickness in male and female rats.
by: Lautridou, Jacky, et al.
Published: (2020)
by: Lautridou, Jacky, et al.
Published: (2020)
Influence of retrogression and re-aging heat treatment to stress corrosion cracking resistance on Al-Zn-Mg-Cu alloy
/ Deraman R., Aziz M. R. And Y. Yaakob
by: Deraman, R., et al.
Published: (2009)
by: Deraman, R., et al.
Published: (2009)
Similar Items
-
Design and synthesis of small molecule inhibitors of coagulation FXIIa
by: Chen, Xi
Published: (2018) -
Crystallographic studies of coagulation factor XII
by: Manna, Rosa
Published: (2016) -
Expression and modulation of tissue factor and tissue factor pathway inhibitor in an endothelial cell based model
by: Ellery, Paul E. R.
Published: (2008) -
Extraction and characterization of Jatropha curcas L. as natural coagulant and its application for turbidity removal
by: Khodapanah, Nasrin
Published: (2014) -
Coagulation of colloidal raw water with Kaolin for water/Siti Rahayu Mohamed
by: Mohamed, Siti Rahayu
Published: (2009)