Design, synthesis, and characterisation of small molecule inhibitors of the coagulation factor XIIa (FXIIa)
Thromboembolic disorders are the major cause of death and disability worldwide. Anticoagulants are the mainstay in the prevention and treatment of thromboembolic diseases. However, almost all the currently available anticoagulants cause therapy-related haemorrhages as a side effect. In the recent ye...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2018
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| Online Access: | https://eprints.nottingham.ac.uk/50895/ |