In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss

Bronchial thermoplasty is a treatment for asthma. Whether during thermoplasty the airway wall fraction exposed to temperatures necessary to affect cells is sufficient to explain its histopathological impact is unclear. Airway smooth muscle and bronchial epithelial cells were exposed to media (37-70...

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Bibliographic Details
Main Authors: Chernyavsky, Igor L., Russell, Richard J., Saunders, Ruth M., Morris, Gavin E., Berair, Rachid, Singapuri, Amisha, Chachi, Latifa, Mansur, Adel H., Howarth, Peter H., Dennison, Paddy, Chaudhuri, Rekha, Bicknell, Stephen, Rose, Felicity R A.J., Siddiqui, Salman, Brook, Bindi S., Brightling, Christopher E.
Format: Article
Published: European Respiratory Society 2018
Subjects:
asthma
bronchial thermoplasty
airway remodelling
airway smooth muscle
bronchial epithelium
bioheat transfer
Online Access:https://eprints.nottingham.ac.uk/50894/

Internet

https://eprints.nottingham.ac.uk/50894/

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