Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia
Bacterial septicaemia is a major cause of mortality, but its pathogenesis remains poorly understood. In experimental pneumococcal murine intravenous infection, an initial reduction of bacteria in the blood is followed hours later by a fatal septicaemia. These events represent a population-bottleneck...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Nature Publishing Group
2018
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| Online Access: | https://eprints.nottingham.ac.uk/50621/ |