Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA

Despite research efforts full potential of siRNA-based therapeutics has not yet been fully realized due to a need for suitable, effective delivery formulations. Here, we examine a potential of a new class of water-soluble chitosans as siRNA platform for pulmonary delivery. The system is based on pip...

Full description

Bibliographic Details
Main Authors: Capel, Victoria, Vllasaliu, Driton, Watts, Peter, Clarke, Philip A., Luxton, Dominic, Grabowska, Anna M., Mantovani, Giuseppe, Stolnik, Snow
Format: Article
Language:English
Published: Taylor & Francis 2018
Subjects:
Online Access:https://eprints.nottingham.ac.uk/50532/