Identifying potential RNA editing sites from RNA-Sequencing data from human brain tissue

RNA A-to-I editing; carried out by the family of adenosine deaminase acting on RNA (ADAR) proteins, is the most common type of RNA editing in vertebrates. It can lead to the disruption of protein synthesis or structure, as well as changes in both the coding and non-coding sequence of the RNA. This c...

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Bibliographic Details
Main Author: North, Francesca Louise
Format: Thesis (University of Nottingham only)
Language:English
Published: 2018
Subjects:
Online Access:https://eprints.nottingham.ac.uk/50506/