Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

G protein-coupled receptors (GPCRs) are physiologically important transmembrane signalling proteins that trigger intracellular responses upon binding of extracellular ligands. Despite recent breakthroughs in GPCR crystallography1–3, the details of ligand induced signal transduction are not well unde...

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Main Authors: Isogai, Shin, Deupi, Xavier, Opitz, Christian, Heydenreich, Franziska M., Tsai, Ching-Ju, Brueckner, Florian, Schertler, Gebhard F.X., Veprintsev, Dmitry B., Grzesiek, Stephan
Format: Article
Published: Nature Publishing Group 2016
Online Access:https://eprints.nottingham.ac.uk/50471/

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https://eprints.nottingham.ac.uk/50471/

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